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2018 2
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Paracrine roles of cellular senescence in promoting tumourigenesis.
Gonzalez-Meljem JM, Apps JR, Fraser HC, Martinez-Barbera JP. Gonzalez-Meljem JM, et al. Br J Cancer. 2018 May;118(10):1283-1288. doi: 10.1038/s41416-018-0066-1. Epub 2018 Apr 19. Br J Cancer. 2018. PMID: 29670296 Free PMC article. Review.
Data-driven identification of ageing-related diseases from electronic health records.
Kuan V, Fraser HC, Hingorani M, Denaxas S, Gonzalez-Izquierdo A, Direk K, Nitsch D, Mathur R, Parisinos CA, Lumbers RT, Sofat R, Wong ICK, Casas JP, Thornton JM, Hemingway H, Partridge L, Hingorani AD. Kuan V, et al. Among authors: fraser hc. Sci Rep. 2021 Feb 3;11(1):2938. doi: 10.1038/s41598-021-82459-y. Sci Rep. 2021. PMID: 33536532 Free PMC article.
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL, Brogan P, Jacques TS, Williams HJ, Martinez-Barbera JP. Apps JR, et al. Among authors: fraser hc. Acta Neuropathol. 2018 May;135(5):757-777. doi: 10.1007/s00401-018-1830-2. Epub 2018 Mar 14. Acta Neuropathol. 2018. PMID: 29541918 Free PMC article.